Which of the following is an indication for surgical treatment of Crohn's disease?

Perforation of the intestine is a critical complication in Crohn's disease that often necessitates surgical intervention. When a section of the bowel becomes perforated, it can lead to contents spilling into the abdominal cavity, resulting in peritonitis, a life-threatening condition. In such cases, the surgical treatment aims to remove the affected segment of the bowel to prevent further complications and stabilize the patient's condition.

While Crohn's disease can be managed effectively with medical therapy, and instances of chronic diarrhea or well-managed hemorrhage may be handled without immediate surgical intervention, perforation represents an acute and severe scenario where surgery is essential for patient survival and health stabilization.